Lower stroke mortality among Hispanics: an exploration of potential methodological confounders

Med Care. 2010 Jun;48(6):534-9. doi: 10.1097/MLR.0b013e3181d686cf.

Abstract

Objectives: Stroke mortality rates are reported to be lower for Hispanics than non-Hispanic Whites. We investigate the degree to which this lower reported mortality is explained by inaccuracies introduced through omission of nativity, imprecise measurement of cause of death, and under-ascertainment of Hispanic ethnicity on death certificates. We used national vital registration data for the years 1989-1991 and 1999-2002, including foreign- and US-born Hispanics and non-Hispanic Whites. Hispanic deaths were adjusted for misclassification of ethnicity on the death certificate. Denominators for the rates were derived from census estimates.

Results: Adjustment for nativity and death certificate misclassification removes the stroke mortality advantage for US-born Hispanic men, but not women. After adjustment, US-born Hispanic men and women have higher rates of mortality from subarachnoid hemorrhage than non-Hispanic Whites (RR: 1.23 and 1.23, respectively), but lower rates of mortality from Ischemic (RR: 0.76 and 0.73, respectively) and chronic effects of stroke (RR: 0.87 and 0.73, respectively).

Conclusions: When adjusted for misclassification the lower stroke mortality remains for Hispanic men and women at older ages. Part of the previously reported advantage is a combination of imprecise measurement and data quality.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Brain Ischemia / ethnology
  • Brain Ischemia / mortality
  • Cerebral Hemorrhage / ethnology
  • Cerebral Hemorrhage / mortality
  • Confounding Factors, Epidemiologic
  • Death Certificates*
  • Female
  • Hispanic or Latino / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Risk Assessment
  • Sex Distribution
  • Stroke / classification
  • Stroke / ethnology*
  • Stroke / mortality*
  • Survival Analysis
  • United States / epidemiology
  • White People / statistics & numerical data*