Differential effects of methylphenidate on problem solving in adults with ADHD

J Atten Disord. 2011 Feb;15(2):161-73. doi: 10.1177/1087054709356391. Epub 2010 May 19.

Abstract

Objective: Two studies were performed to assess both divergent and convergent thinking in adults with ADHD.

Method: The first study compared the problem-solving abilities of healthy participants (N = 144) and unmedicated adults with ADHD (N = 144). In the second study, problem-solving abilities of adults with diagnosed ADHD (N = 22) were examined twice, that is, on and off methylphenidate (MPH), and compared with the performance of a healthy control group (N = 22). Convergent thinking was measured using a Tower of London task, whereas divergent thinking was assessed using verbal fluency tasks.

Results: Adults with ADHD off MPH displayed marked deficits of both divergent and convergent thinking. MPH treatment resulted in a marked improvement of convergent thinking, while no effect of medication was found regarding divergent thinking.

Conclusion: Pharmacological treatment of adults with ADHD revealed a differential effect of MPH on problem solving abilities.

MeSH terms

  • Adult
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Central Nervous System Stimulants / therapeutic use*
  • Female
  • Humans
  • Male
  • Methylphenidate / pharmacology
  • Methylphenidate / therapeutic use*
  • Neuropsychological Tests
  • Problem Solving / drug effects*

Substances

  • Central Nervous System Stimulants
  • Methylphenidate