We describe the use of multiple Amplatzer vascular plugs which were intentionally placed so as to isolate a large azygous vein aneurysm with intraluminal thrombosis, which had resulted in a previous pulmonary embolus. This technique avoided the need for an invasive thoracotomy and aneurysm resection or attempting to directly fill the large aneurysm with numerous and various embolization devices.
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