Late reuse of liver allografts from brain-dead graft recipients: the Munich experience and a review of the literature

Liver Transpl. 2010 Jun;16(6):701-4. doi: 10.1002/lt.22053.

Abstract

The increasing donor organ shortage requires the consideration of any possible organ donor in order to meet the current demand. However, the growing number of long-term survivors of liver transplantation may create a situation in which former organ recipients may experience brain death with a functioning graft and therefore become organ donors themselves. Previous reports concerning this rare situation predominantly refer to the reuse of donor organs within the first 8 days after primary liver transplantation. So far, only a single case of late reuse of a donor liver has been published, with 2 additional cases mentioned in a summary of the United Network for Organ Sharing database. Here we report the case of a 43-year-old female donor who had received a liver graft for complications of Budd-Chiari syndrome 5 years before becoming an organ donor herself after cerebral infarction with consecutive brain death.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Brain Death*
  • Budd-Chiari Syndrome / surgery
  • Cerebral Infarction*
  • Cysts / surgery
  • Female
  • Germany
  • Graft Survival*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Liver Diseases / surgery*
  • Liver Transplantation*
  • Middle Aged
  • Reoperation
  • Time Factors
  • Tissue Donors / supply & distribution*
  • Transplantation, Homologous

Substances

  • Immunosuppressive Agents