Moyamoya: epidemiology, presentation, and diagnosis

Edward R Smith; R Michael Scott

doi:10.1016/j.nec.2010.03.007

Moyamoya: epidemiology, presentation, and diagnosis

Neurosurg Clin N Am. 2010 Jul;21(3):543-51. doi: 10.1016/j.nec.2010.03.007.

Authors

Edward R Smith¹, R Michael Scott

Affiliation

¹ Department of Neurosurgery, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. edward.smith@childrens.harvard.edu

PMID: 20561502
DOI: 10.1016/j.nec.2010.03.007

Abstract

Moyamoya syndrome is an increasingly recognized arteriopathy associated with cerebral ischemia and has been associated with approximately 6% of childhood strokes. It is characterized by chronic progressive stenosis at the apices of the intracranial internal carotid arteries, including the proximal anterior cerebral arteries and middle cerebral arteries and ultimately results in decreased cerebral blood flow with an increased resultant risk of stroke. This article discusses the epidemiology, presentation, and diagnosis of this condition in children.

Publication types

Review

MeSH terms

Brain Ischemia / etiology
Brain Ischemia / prevention & control
Brain Ischemia / therapy
Carotid Stenosis / diagnosis*
Carotid Stenosis / physiopathology*
Carotid Stenosis / therapy
Cerebral Arteries / diagnostic imaging*
Cerebral Arteries / pathology*
Cerebral Arteries / physiopathology
Cerebral Revascularization / methods
Cerebral Revascularization / standards
Child
Diagnosis, Differential
Diagnostic Imaging
Humans
Moyamoya Disease / diagnosis*
Moyamoya Disease / physiopathology*
Moyamoya Disease / therapy
Radiography
Stroke / etiology
Stroke / prevention & control
Stroke / therapy