Reversible cerebral vasoconstriction syndrome associated with hormone therapy for intrauterine insemination

Cephalalgia. 2010 Sep;30(9):1127-32. doi: 10.1177/0333102409360675. Epub 2010 Mar 31.

Abstract

Introduction: Reversible cerebral vasoconstriction syndrome (RCVS) comprises a heterogeneous group of acute neurological diseases which are characterized by thunderclap headache and evidence of reversible multifocal constriction of cerebral arteries. A number of precipitating factors have been described in the literature, including recent childbirth and use of vasoactive substances.

Case description: Here we present the case of a female patient with RCVS which occurred in the setting of hormonal ovarian stimulation for intrauterine insemination.

Discussion: This case possibly contributes to the understanding of the pathophysiological mechanisms underlying reversible cerebral vasoconstriction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebrovascular Circulation / drug effects*
  • Chorionic Gonadotropin / adverse effects*
  • Female
  • Follicle Stimulating Hormone / adverse effects*
  • Headache Disorders, Primary / chemically induced*
  • Headache Disorders, Primary / pathology
  • Humans
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Ovulation Induction / adverse effects
  • Vasoconstriction / drug effects*
  • Vasospasm, Intracranial / chemically induced*
  • Vasospasm, Intracranial / pathology

Substances

  • Chorionic Gonadotropin
  • Follicle Stimulating Hormone