Objective: To develop clinical risk tools for preeclampsia and small for gestational age (SGA) in high-risk women.
Methods: Individual risk scores based on clinical risk factors were calculated using logistic regression and validated in 1687 women with obesity in first pregnancy, chronic hypertension, or previous preeclampsia.
Results: The risk of preeclampsia varied from 7% in obese primiparae without hypertension to 30% when previous preeclampsia and chronic hypertension occurred together. A prediction model incorporating these risk factors had a sensitivity of 48 and 89% for preeclampsia delivered <34 weeks' gestation.
Conclusion: Multiple clinical risk factors increase the risk of preeclampsia and SGA.