Abstract
We describe a case series of 17 patients hospitalized in Manaus (western Brazilian Amazon) with PCR-confirmed Plasmodium vivax infection who were treated with chloroquine and primaquine. The major complications were jaundice and severe anemia. No in vivo chloroquine resistance was detected. These data help characterize the clinical profile of severe P. vivax malaria in Latin America.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Antimalarials / therapeutic use
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Brazil / epidemiology
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Child
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Child, Preschool
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Chloroquine / therapeutic use
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Female
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Humans
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Infant
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Infant, Newborn
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Malaria, Vivax / drug therapy
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Malaria, Vivax / epidemiology*
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Malaria, Vivax / parasitology
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Malaria, Vivax / physiopathology*
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Male
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Middle Aged
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Plasmodium vivax / classification
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Plasmodium vivax / drug effects
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Plasmodium vivax / genetics
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Plasmodium vivax / isolation & purification*
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Polymerase Chain Reaction / methods
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Primaquine / therapeutic use
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Severity of Illness Index
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Young Adult
Substances
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Antimalarials
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Chloroquine
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Primaquine