[Acute cytomegalovirus infection revealing systemic lupus erythematosus]

Rev Med Interne. 2011 Jan;32(1):e6-8. doi: 10.1016/j.revmed.2010.03.456. Epub 2010 Sep 28.
[Article in French]

Abstract

Systemic lupus erythematosus (SLE) remains of unknown origin. Herpes viridae infections seem to play a role in the pathogenesis of this disease. We report a 31-year-old man who presented an acute cytomegalovirus (CMV) infection with persistent fever and myopericarditis as the presenting manifestation of SLE. This case report emphasizes a difficult differential diagnosis between SLE and an acute CMV infection and suggests a possible role of this virus in the pathogenesis of SLE.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Adult
  • Antimalarials / therapeutic use
  • Antirheumatic Agents / therapeutic use
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / drug therapy
  • Cytomegalovirus* / isolation & purification
  • Cytomegalovirus* / pathogenicity
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Fever / virology
  • Glucocorticoids / therapeutic use
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / virology*
  • Male
  • Myocarditis / virology
  • Pericarditis / virology
  • Treatment Outcome

Substances

  • Antimalarials
  • Antirheumatic Agents
  • Glucocorticoids