Alpha1-antitrypsin deficiency and autophagy

N Engl J Med. 2010 Nov 4;363(19):1863-4. doi: 10.1056/NEJMcibr1008007.
No abstract available

MeSH terms

  • Animals
  • Anticonvulsants / pharmacology*
  • Anticonvulsants / therapeutic use
  • Autophagy / drug effects*
  • Carbamazepine / pharmacology*
  • Carbamazepine / therapeutic use
  • Humans
  • Liver / metabolism
  • Liver / pathology
  • Liver Cirrhosis / drug therapy*
  • Liver Cirrhosis / pathology
  • Mice
  • Mutant Proteins / chemistry
  • Mutant Proteins / metabolism
  • Mutation
  • Protein Folding
  • alpha 1-Antitrypsin / chemistry
  • alpha 1-Antitrypsin / genetics
  • alpha 1-Antitrypsin / metabolism*
  • alpha 1-Antitrypsin Deficiency / drug therapy*
  • alpha 1-Antitrypsin Deficiency / metabolism

Substances

  • Anticonvulsants
  • Mutant Proteins
  • alpha 1-Antitrypsin
  • Carbamazepine