Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature

Dermatol Online J. 2010 Oct 15;16(10):2.

Abstract

In rare cases, cutaneous larva migrans may be complicated by Löffler syndrome. This syndrome is thought to result from a type I hypersensitivity reaction related to the pulmonary larval migration phase of various parasites. It is characterized by migratory pulmonary eosinophilic infiltrates and peripheral eosinophilia, with malaise, fever, and cough. Our patient was successfully treated with ivermectin, a corticosteroid cream, and inhalation medication in an early phase, which prevented complications. We present the details of this case and review the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Anti-Asthmatic Agents / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Antiparasitic Agents / therapeutic use
  • Budesonide / therapeutic use
  • Budesonide, Formoterol Fumarate Drug Combination
  • Clobetasol / therapeutic use
  • Drug Combinations
  • Ethanolamines / therapeutic use
  • Humans
  • Ivermectin / therapeutic use
  • Larva Migrans / complications*
  • Larva Migrans / drug therapy
  • Male
  • Pulmonary Eosinophilia / diagnosis*
  • Pulmonary Eosinophilia / drug therapy
  • Pulmonary Eosinophilia / etiology*

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents
  • Anti-Inflammatory Agents
  • Antiparasitic Agents
  • Budesonide, Formoterol Fumarate Drug Combination
  • Drug Combinations
  • Ethanolamines
  • Budesonide
  • Ivermectin
  • Clobetasol