Human blood group genes 2010: chromosomal locations and cloning strategies revisited

Lennart Lögdberg; Marion E Reid; Teresa Zelinski

doi:10.1016/j.tmrv.2010.08.005

Human blood group genes 2010: chromosomal locations and cloning strategies revisited

Transfus Med Rev. 2011 Jan;25(1):36-46. doi: 10.1016/j.tmrv.2010.08.005.

Authors

Lennart Lögdberg¹, Marion E Reid, Teresa Zelinski

Affiliation

¹ Center for Transfusion and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.

PMID: 21134625
DOI: 10.1016/j.tmrv.2010.08.005

Abstract

Thirty human blood group systems are now recognized. Corresponding genes have been cloned and characterized for all of the systems and localized to single cytogenetic bands on 14 autosomes and the X chromosome. In this review, we summarize this information, highlighting the most recently defined blood group system (Rh-associated glycoprotein) and the developing understanding of the P1 system and the complex molecular basis for its phenotypes.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Blood Group Antigens / genetics*
Blood Group Antigens / isolation & purification
Blood Grouping and Crossmatching / methods
Chromosome Mapping / methods*
Cloning, Molecular / methods*
Humans
Time Factors

Substances

Blood Group Antigens