Role of EGF inhibitors in the treatment of recurrent or metastatic squamous cell head and neck cancer

Cancer Manag Res. 2009 Nov 3:1:151-4. doi: 10.2147/cmr.s5134.

Abstract

Squamous cell cancer of the head and neck (SCCHN) is a major contributor to morbidity and mortality worldwide. In recent years, inhibition of the epidermal growth factor receptor has become an established treatment strategy in SCCHN both in the up-front treatment and in the recurrent and metastatic setting. This review summarizes the most important developments of the recent past and provides an overview of newer developments.

Keywords: epidermal growth factor receptor; head; neck; squamous cell cancer.