Two stage revision knee arthroplasty for infection with massive bone loss. A technique to achieve spacer stability

Knee. 2012 Jan;19(1):24-7. doi: 10.1016/j.knee.2010.12.002. Epub 2011 Jan 6.

Abstract

We report a technique for the intra-operative production of an antibiotic-impregnated cement spacer, reinforced with an intramedullary nail. The spacer is designed for use in cases where significant bone loss and/or ligamentous instability prevent the formation of a stable joint when using a conventional spacer during a two-stage revision knee arthroplasty. This technique has been performed in eleven patients. Nine patients have subsequently undergone a second-stage procedure. Two patients died of unrelated causes before a second-stage could be performed. In all but one case, the infection has been successfully eradicated and patients remain infection free at a mean follow-up of 32 months (range 21-64 months). We believe that the described technique is an effective alternative to the traditional spacer, in patients with significant bone loss and/or ligamentous instability. It delivers antibiotics locally, while producing a mechanically stable joint, on which the patient can mobilise, maintaining leg length and tissue tensions.

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Arthroplasty, Replacement, Knee / adverse effects*
  • Bone Cements*
  • Bone Nails
  • Drug Implants
  • Female
  • Humans
  • Knee Joint / pathology
  • Knee Joint / physiopathology
  • Knee Joint / surgery
  • Knee Prosthesis*
  • Male
  • Middle Aged
  • Prosthesis Design*
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / surgery*
  • Recovery of Function
  • Reoperation
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Bone Cements
  • Drug Implants