Abstract
Vitamin D deficiency is common in chronic kidney disease and is associated with increased morbidity and mortality. In addition, vitamin D deficiency in renal disease is associated with serious comorbidities including secondary hyperparathyroidism and cardiovascular disease. Several therapeutic options are available to correct vitamin D deficiency, including nutritional vitamin D, pro-hormones and active hormones. In this review we discuss clinical findings related to the effectiveness of these therapies in chronic kidney disease.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Cardiovascular Diseases / drug therapy*
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Cardiovascular Diseases / etiology
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Cardiovascular Diseases / metabolism
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Disease Progression
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Humans
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Hyperparathyroidism, Secondary / drug therapy*
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Hyperparathyroidism, Secondary / etiology
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Hyperparathyroidism, Secondary / metabolism
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Kidney Failure, Chronic / complications
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Kidney Failure, Chronic / drug therapy*
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Kidney Failure, Chronic / metabolism
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Vitamin D / metabolism
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Vitamin D / therapeutic use*
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Vitamin D Deficiency / drug therapy*
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Vitamin D Deficiency / etiology
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Vitamin D Deficiency / metabolism