Acute stroke intervention

Alexander A Khalessi; Sabareesh K Natarajan; David Orion; Mandy J Binning; Adnan Siddiqui; Elad I Levy; L Nelson Hopkins

doi:10.1016/j.jcin.2010.11.015

Acute stroke intervention

JACC Cardiovasc Interv. 2011 Mar;4(3):261-9. doi: 10.1016/j.jcin.2010.11.015.

Authors

Alexander A Khalessi¹, Sabareesh K Natarajan, David Orion, Mandy J Binning, Adnan Siddiqui, Elad I Levy, L Nelson Hopkins

Affiliation

¹ Department of Neurosurgery and Toshiba Stroke Research Center, University at Buffalo, State University of New York, USA.

PMID: 21435602
DOI: 10.1016/j.jcin.2010.11.015

Abstract

This review summarizes the current state-of-the-art regarding the endovascular management of acute ischemic stroke. Beginning with intravenous tissue plasminogen activator, this paper traces the gradual shift of systemic thrombolysis from a competing to complementary treatment modality. Intra-arterial thrombolysis, mechanical thrombectomy with the Merci (Concentric Medical, Mountain View, California) and Penumbra (Penumbra, Inc., Alameda, California) systems, angioplasty, primary intracranial stenting, and emerging stentriever devices are sequentially reviewed. Ultimately, this paper lays the foundation for current endovascular stroke management and considers future areas of progress and research.

Publication types

Review

MeSH terms

Angioplasty / instrumentation
Endovascular Procedures* / adverse effects
Endovascular Procedures* / instrumentation
Equipment Design
Humans
Patient Selection
Prosthesis Design
Risk Assessment
Severity of Illness Index
Stents
Stroke / diagnosis
Stroke / epidemiology
Stroke / therapy*
Thrombectomy / instrumentation
Thrombolytic Therapy
Time Factors
Treatment Outcome