Regression of HIV-associated grade IV T cell lymphoma with combined antiretroviral therapy only

Int J Hematol. 2011 Jun;93(6):811-814. doi: 10.1007/s12185-011-0859-y. Epub 2011 May 11.

Abstract

The present report describes repeated long-term remissions of a high-grade T cell lymphoma in an HIV-positive patient upon cART only, without additional chemotherapy. A review of cases from the literature further illustrates the anti-tumor effects of cART through the induction of a strong immune reconstitution in HIV-infected patients.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active
  • Bone and Bones / pathology
  • CD4 Lymphocyte Count
  • HIV Infections / complications
  • Humans
  • Lymphoma, AIDS-Related / diagnosis
  • Lymphoma, AIDS-Related / drug therapy*
  • Lymphoma, AIDS-Related / pathology*
  • Lymphoma, T-Cell / diagnosis
  • Lymphoma, T-Cell / drug therapy*
  • Lymphoma, T-Cell / pathology*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Positron-Emission Tomography
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Viral Load

Substances

  • Anti-HIV Agents