Higher infant body fat with excessive gestational weight gain in overweight women

Am J Obstet Gynecol. 2011 Sep;205(3):211.e1-7. doi: 10.1016/j.ajog.2011.04.004. Epub 2011 Apr 14.

Abstract

Objective: Gestational weight gain (GWG) is positively associated with birthweight and maternal prepregnancy body mass index (BMI) is directly related to infant fat mass (FM). This study examined whether differences exist in infant body composition based on 2009 GWG recommendations.

Study design: Body composition was measured in 306 infants, and GWG was categorized as appropriate or excessive. Analysis of covariance was used to investigate the effects of GWG and prepregnancy BMI and their interaction on infant body composition.

Results: Within the appropriate group, infants from obese mothers had greater percent fat (%fat) and FM than offspring from normal and overweight mothers. Within the excessive group, infants from normal mothers had less %fat and FM than infants from overweight and obese mothers. A difference was found for %fat and FM within the overweight group between GWG categories.

Conclusion: Excessive GWG is associated with greater infant body fat and the effect is greatest in overweight women.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adiposity / physiology*
  • Adult
  • Body Mass Index
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Obesity / physiopathology
  • Overweight / physiopathology*
  • Pregnancy
  • Prospective Studies
  • Weight Gain / physiology*