Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers

Org Biomol Chem. 2011 Jul 7;9(13):4770-3. doi: 10.1039/c1ob05473b. Epub 2011 May 31.

Abstract

A bifunctionalised carboxymethyl-cellulose polymer bearing adamantane units and an antigenic fragment forms a highly stable interfacial complex with a βCD-containing surface. This allows the highly sensitive detection of antibodies using an amperometric immunosensor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies / blood*
  • Antibodies / immunology
  • Antigens / chemistry*
  • Antigens / immunology
  • Cellulose / chemistry*
  • Cyclodextrins / chemistry*
  • Molecular Structure

Substances

  • Antibodies
  • Antigens
  • Cyclodextrins
  • Cellulose