Reliability and validity of a new sexual function questionnaire (Nagoya Sexual Function Questionnaire) for schizophrenic patients taking antipsychotics

Hum Psychopharmacol. 2011 Jun-Jul;26(4-5):300-6. doi: 10.1002/hup.1205. Epub 2011 Jun 22.

Abstract

Objective: This study aims to validate a new user-friendly sexual function questionnaire (Nagoya Sexual Function Questionnaire [NSFQ]) for schizophrenic patients taking antipsychotics.

Methods: Schizophrenic outpatients (men = 30, women = 30) were asked to fill out the NSFQ at initial entry into the research program (Time₁) and again 1 to 2 weeks later (Time₂). To assess the convergent validity of the NSFQ, at Time₁, subjects were asked to fill out the Japanese version of the Udvalg for Kliniske Undersogekser Side Effect Rating Scale (UKU). To assess the discriminant validity of the NSFQ, at Time₁, subjects were also asked to fill out the Japanese version of Epworth Sleepiness Scale.

Results: Results from Cronbach's alpha analysis indicated that the NSFQ demonstrated excellent internal consistency and scale reliability. The NSFQ also demonstrated strong test-retest reliability. The NSFQ total score was highly correlated with the UKU total score. The NSFQ was shown to have good convergent validity with the UKU. The NSFQ total score was not correlated with the Japanese version of Epworth Sleepiness Scale total score.

Conclusions: This study revealed the internal consistency, test-retest reliability, and convergent and discriminant validities of the NSFQ.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Galactorrhea / chemically induced
  • Galactorrhea / diagnosis*
  • Galactorrhea / psychology
  • Gynecomastia / chemically induced
  • Gynecomastia / complications
  • Gynecomastia / diagnosis*
  • Gynecomastia / psychology
  • Humans
  • Japan
  • Male
  • Menstruation Disturbances / chemically induced
  • Menstruation Disturbances / complications
  • Menstruation Disturbances / diagnosis*
  • Menstruation Disturbances / psychology
  • Middle Aged
  • Reproducibility of Results
  • Schizophrenia / complications
  • Schizophrenia / drug therapy*
  • Sexual Dysfunction, Physiological / chemically induced
  • Sexual Dysfunction, Physiological / complications
  • Sexual Dysfunction, Physiological / diagnosis*
  • Sexual Dysfunction, Physiological / psychology
  • Sexual Dysfunctions, Psychological / chemically induced
  • Sexual Dysfunctions, Psychological / complications
  • Sexual Dysfunctions, Psychological / diagnosis*
  • Sexual Dysfunctions, Psychological / psychology
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Antipsychotic Agents