The INHERITANCE project, funded by the European Commission, is aimed at studying genetic or inherited Dilated cardiomyopathies (DCM) and at understanding the impact and management of the condition within families that suffer from heart conditions that are caused by DCMs. The project is supported by a number of advanced biomedical informatics tools, including data warehousing, automated literature search and decision support. The paper describes the design of these tools and the current status of implementation.