Liposome immunoassay for rapid identification of group A streptococci directly from throat swabs

M A Gerber; M F Randolph; K K DeMeo

doi:10.1128/jcm.28.6.1463-1464.1990

Liposome immunoassay for rapid identification of group A streptococci directly from throat swabs

J Clin Microbiol. 1990 Jun;28(6):1463-4. doi: 10.1128/jcm.28.6.1463-1464.1990.

Authors

M A Gerber¹, M F Randolph, K K DeMeo

Affiliation

¹ Department of Pediatrics, University of Connecticut Health Center, Farmington 06032.

Abstract

The Q Test Strep (Becton Dickinson and Co., Franklin Lakes, N.J.) is a new solid-phase liposome immunoassay for the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis. Compared with blood agar plate cultures, the Q Test Strep had a sensitivity of 91%, a specificity of 83%, a positive predictive value of 88%, and a negative predictive value of 87%. Liposome technology can be used to facilitate the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis.

MeSH terms

Humans
Immunoassay*
Liposomes*
Pharyngitis / complications
Pharyngitis / diagnosis*
Pharyngitis / microbiology
Sensitivity and Specificity
Streptococcal Infections / complications
Streptococcal Infections / diagnosis*
Streptococcus pyogenes / isolation & purification*

Substances

Liposomes