Vogt-Koyanagi-Harada syndrome in a 6-year-old Hispanic boy

Pediatr Dermatol. 2012 Mar-Apr;29(2):191-4. doi: 10.1111/j.1525-1470.2011.01571.x. Epub 2011 Oct 13.

Abstract

A 6-year-old Hispanic boy presented to the ophthalmology department with complaints of pain, photophobia, and blurry vision of both eyes. He was found to have bilateral granulomatous panuveitis, cataracts, and high intraocular pressures. He later developed multiple asymptomatic, ovoid, hypopigmented patches over the mid-lumbosacral back. Biopsy of lesional skin was significant for low melanocyte counts and a mild lymphocytic infiltrate. The patient was diagnosed with Vogt-Koyanagi-Harada syndrome (VKH). This article reviews the literature regarding the cutaneous presentation of VKH.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child
  • Fluprednisolone / analogs & derivatives
  • Fluprednisolone / therapeutic use
  • Humans
  • Hypopigmentation / diagnosis
  • Male
  • Methotrexate / therapeutic use
  • Ophthalmic Solutions / therapeutic use
  • Timolol / therapeutic use
  • Treatment Outcome
  • Uveomeningoencephalitic Syndrome / diagnosis*
  • Uveomeningoencephalitic Syndrome / drug therapy

Substances

  • Ophthalmic Solutions
  • Timolol
  • Fluprednisolone
  • difluprednate
  • Methotrexate