Depression is one of the most commonly diagnosed psychological health problems and a major cause of disability in this country. Very little attention, however, has been given to depression among Latinos. To address this issue, the authors provide a review of the literature on psychosocial factors that contribute to depression within the Latino adult population. In addition, the authors argue that Behavioral Activation (BA), as an alternative treatment approach, may be as effective as, if not more effective than, Cognitive Behavioral Therapy because of BA's focus on environmental conditions and behavior change rather than beliefs and underlying attitudes. More importantly, components of BA can be easily adapted to accommodate specific Latino cultural values. Its application is illustrated in a case example. (PsycINFO Database Record (c) 2010 APA, all rights reserved).