Presumed necrotizing viral retinitis after intravitreal triamcinolone injection: case report

Korean J Ophthalmol. 2011 Dec;25(6):451-4. doi: 10.3341/kjo.2011.25.6.451. Epub 2011 Nov 22.

Abstract

A 56-year-old man presented with anterior chamber inflammation, increased intraocular pressure, peripheral retinal infiltration, and generalized retinal arterial obstruction suggesting acute retinal necrosis five months after intravitreal triamcinolone acetonide injection (IVTA). He was treated with intravenous antiviral agents and aspirin. Shortly after treatment, retinal infiltrations were resolved, and partial recanalization of the obstructed vessel was observed. Viral retinitis may occur as an opportunistic infection following IVTA due to the local immune modulatory effect of the steroid; hence, close observation following IVTA is necessary.

Keywords: Acute retinal necrosis; Herpetic retinitis; Intravitreal injections; Intravitreal triamcinolone acetonide injection.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antiviral Agents / therapeutic use
  • Aspirin / therapeutic use
  • Drug Therapy, Combination
  • Humans
  • Intravitreal Injections
  • Male
  • Middle Aged
  • Opportunistic Infections / chemically induced*
  • Opportunistic Infections / virology
  • Retinal Necrosis Syndrome, Acute / chemically induced*
  • Retinal Necrosis Syndrome, Acute / virology
  • Triamcinolone Acetonide / administration & dosage
  • Triamcinolone Acetonide / adverse effects*

Substances

  • Antiviral Agents
  • Triamcinolone Acetonide
  • Aspirin