Prediction of cognitive abilities at the age of 5 years using developmental follow-up assessments at the age of 2 and 3 years in very preterm children

Dev Med Child Neurol. 2012 Mar;54(3):240-6. doi: 10.1111/j.1469-8749.2011.04181.x. Epub 2011 Dec 21.

Abstract

Aim: This study investigated prediction of separate cognitive abilities at the age of 5 years by cognitive development at the ages of both 2 and 3 years, and the agreement between these measurements, in very preterm children.

Methods: Preterm children (n=102; 44 males; 58 females) with a gestational age less than 30 weeks and/or birthweight less than 1000g were assessed at the ages of 2 and 3 years using the second edition of the Bayley Scales of Infant Development, the Child Behaviour Checklist, and a neurological examination, and at the age of 5 years using the third edition of the Wechsler Preschool and Primary Scale of Intelligence.

Results: Cognitive development at ages 2 and 3 years explained 44% and 57% respectively of full-scale intelligence at the age of 5 years. Adding psychomotor, neurological, and behavioural outcomes to the regression model could not or only marginally improve the prediction; adding perinatal and sociodemographic characteristics to the regression model increased the explained variance to 57% and 64% respectively. These percentages were comparable for verbal intelligence. Processing speed quotient and especially performance intelligence were predicted less accurately.

Interpretation: Not all aspects of intelligence are predicted sufficiently by the Mental Development Index at ages 2 and 3 years. Follow-up of very preterm children until at least the age of 5 years is needed to distinguish between different aspects of cognitive development.

MeSH terms

  • Behavioral Symptoms / diagnosis
  • Behavioral Symptoms / etiology
  • Child, Preschool
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology*
  • Developmental Disabilities / physiopathology*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Longitudinal Studies
  • Male
  • Neurologic Examination
  • Neuropsychological Tests
  • Predictive Value of Tests
  • Premature Birth
  • Statistics as Topic