Topical tacrolimus induced extensive varicella zoster infection

Dermatol Online J. 2011 Dec 15;17(12):5.

Abstract

Tacrolimus ointment 0.1 percent is a well-established topical therapy for treating atopic dermatitis. Efficacy and safety have been described in several trials. Here, we present a patient with rapid onset of extensive varicella zoster infection in tacrolimus-treated skin: a side effect that has only occasionally been reported. Early recognition is important because rapid treatment for herpes zoster may lead to less frequent post-herpetic neuralgia and serious complications.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / analogs & derivatives
  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Dermatitis, Atopic / drug therapy
  • Dermatologic Agents / adverse effects*
  • Dermatologic Agents / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Fusidic Acid / therapeutic use
  • Herpes Zoster / chemically induced*
  • Herpes Zoster / diagnosis
  • Herpes Zoster / drug therapy
  • Herpesvirus 3, Human / drug effects
  • Herpesvirus 3, Human / isolation & purification*
  • Humans
  • Middle Aged
  • Ointments
  • Tacrolimus / adverse effects*
  • Tacrolimus / therapeutic use
  • Treatment Outcome
  • Valacyclovir
  • Valine / analogs & derivatives
  • Valine / therapeutic use

Substances

  • Antiviral Agents
  • Dermatologic Agents
  • Ointments
  • Fusidic Acid
  • Valine
  • Valacyclovir
  • Tacrolimus
  • Acyclovir