Abstract
Tacrolimus ointment 0.1 percent is a well-established topical therapy for treating atopic dermatitis. Efficacy and safety have been described in several trials. Here, we present a patient with rapid onset of extensive varicella zoster infection in tacrolimus-treated skin: a side effect that has only occasionally been reported. Early recognition is important because rapid treatment for herpes zoster may lead to less frequent post-herpetic neuralgia and serious complications.
MeSH terms
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Acyclovir / analogs & derivatives
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Acyclovir / therapeutic use
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Antiviral Agents / therapeutic use
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Dermatitis, Atopic / drug therapy
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Dermatologic Agents / adverse effects*
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Dermatologic Agents / therapeutic use
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Drug Therapy, Combination
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Female
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Fusidic Acid / therapeutic use
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Herpes Zoster / chemically induced*
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Herpes Zoster / diagnosis
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Herpes Zoster / drug therapy
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Herpesvirus 3, Human / drug effects
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Herpesvirus 3, Human / isolation & purification*
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Humans
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Middle Aged
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Ointments
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Tacrolimus / adverse effects*
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Tacrolimus / therapeutic use
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Treatment Outcome
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Valacyclovir
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Valine / analogs & derivatives
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Valine / therapeutic use
Substances
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Antiviral Agents
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Dermatologic Agents
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Ointments
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Fusidic Acid
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Valine
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Valacyclovir
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Tacrolimus
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Acyclovir