Recurrence after successful treatment among patients with multidrug-resistant tuberculosis

J Lee; H-J Lim; Y-J Cho; Y S Park; S-M Lee; S-C Yang; C-G Yoo; Y W Kim; S K Han; J-J Yim

doi:10.5588/ijtld.11.0098

Recurrence after successful treatment among patients with multidrug-resistant tuberculosis

Int J Tuberc Lung Dis. 2011 Oct;15(10):1331-3. doi: 10.5588/ijtld.11.0098.

Authors

J Lee¹, H-J Lim, Y-J Cho, Y S Park, S-M Lee, S-C Yang, C-G Yoo, Y W Kim, S K Han, J-J Yim

Affiliation

¹ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.

PMID: 22283890
DOI: 10.5588/ijtld.11.0098

Abstract

A retrospective review was conducted of patients with multidrug-resistant tuberculosis (MDR-TB) to elucidate the rate of recurrence after successful treatment. Of 123 MDR-TB patients, 90 were declared as 'cured' or 'treatment completed' after individualised treatment; four (4.4%) experienced recurrence. All patients with recur- rent MDR-TB were documented as 'treatment completed' after treatment. Recurrence of MDR-TB is possible after successful treatment, particularly among those documented as 'treatment completed'.

MeSH terms

Adult
Aged
Antitubercular Agents / therapeutic use*
Chi-Square Distribution
Drug Resistance, Multiple, Bacterial*
Female
Humans
Kaplan-Meier Estimate
Male
Microbial Sensitivity Tests
Middle Aged
Mycobacterium tuberculosis / drug effects*
Mycobacterium tuberculosis / isolation & purification
Recurrence
Republic of Korea
Retrospective Studies
Sputum / microbiology
Time Factors
Treatment Outcome
Tuberculosis, Multidrug-Resistant / diagnosis
Tuberculosis, Multidrug-Resistant / drug therapy*
Tuberculosis, Multidrug-Resistant / microbiology
Tuberculosis, Pulmonary / diagnosis
Tuberculosis, Pulmonary / drug therapy*
Tuberculosis, Pulmonary / microbiology

Substances

Antitubercular Agents