Infectious complications in GSW's through the gastrointestinal tract into the spine

Injury. 2012 Jul;43(7):1058-60. doi: 10.1016/j.injury.2012.01.014. Epub 2012 Feb 4.

Abstract

Background: Trans-gastrointestinal tract GSW's to the spine are devastating injuries with significant potential for infectious complications. We sought to address antimicrobial management of these injuries.

Methods: We retrospectively analysed all patients with penetrating trauma through the GI tract into the spine admitted to a level I trauma centre from 1/02 to 12/09. Patients were excluded if they died within 24h. Patients received 24-48 h of peri-operative prophylactic antibiotics, except in damage control where antibiotics were continued until packs were removed.

Results: 51 patients were included. 94% were male with a mean age of 27 years. The mean ISS was 28 (9-50). The mean length of stay was 19 days (3-53) and mortality was 9.8%. The mean follow up period was 277 days (0-1765). There were 12 gastric, 25 small bowel, 26 colonic, and 4 esophageal injuries. There were 48 exploratory laparotomies, of which 12 were damage control procedures. 18 patients had no infections. There were 20 abdominal infections and 7 surgical wound infections. There were 23 infections not related to the abdomen. One patient developed a CNS infection 4 days after discharge despite receiving a two week course of piperacillin/tazobactam for Escherichia coli bacteremia during his initial hospital stay. There were no other CNS infections.

Conclusion: Despite the potential for significant deep infections of the spine, standard antimicrobial prophylaxis is sufficient for the initial management of these patients.

MeSH terms

  • Abdominal Injuries
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / administration & dosage*
  • Antibiotic Prophylaxis*
  • Female
  • Follow-Up Studies
  • Gastrointestinal Tract / injuries*
  • Humans
  • Intestinal Perforation / etiology*
  • Intestinal Perforation / mortality
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Retrospective Studies
  • Spinal Injuries / complications*
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / mortality
  • Trauma Centers
  • Wounds, Gunshot / complications*
  • Wounds, Gunshot / mortality
  • Young Adult

Substances

  • Anti-Bacterial Agents