Enduring response to everolimus as third-line therapy in a patient with advanced renal cell carcinoma, including small-bowel metastases: loss of FHIT but normal VHL gene status

Clin Genitourin Cancer. 2012 Sep;10(3):202-6. doi: 10.1016/j.clgc.2012.01.008. Epub 2012 Mar 21.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Acid Anhydride Hydrolases / genetics*
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Renal Cell / diagnostic imaging
  • Carcinoma, Renal Cell / drug therapy
  • Carcinoma, Renal Cell / genetics
  • Carcinoma, Renal Cell / secondary*
  • Everolimus
  • Gene Deletion
  • Humans
  • In Situ Hybridization, Fluorescence
  • Jejunal Neoplasms / diagnostic imaging
  • Jejunal Neoplasms / drug therapy
  • Jejunal Neoplasms / genetics
  • Jejunal Neoplasms / secondary*
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / drug therapy
  • Kidney Neoplasms / genetics
  • Kidney Neoplasms / pathology*
  • Male
  • Middle Aged
  • Neoplasm Proteins / genetics*
  • Radiography
  • Sirolimus / analogs & derivatives*
  • Sirolimus / therapeutic use
  • Treatment Outcome
  • Von Hippel-Lindau Tumor Suppressor Protein / genetics*

Substances

  • Antineoplastic Agents
  • Neoplasm Proteins
  • fragile histidine triad protein
  • Everolimus
  • Von Hippel-Lindau Tumor Suppressor Protein
  • Acid Anhydride Hydrolases
  • VHL protein, human
  • Sirolimus