Endocarditis with ruptured sinus of Valsalva aneurysm caused by nonvaccine Streptococcus pneumoniae serotype 21

Tex Heart Inst J. 2012;39(2):277-80.

Abstract

Sinus of Valsalva aneurysm is a rare, catastrophic complication of endocarditis. We report an unusual case of ruptured sinus of Valsalva aneurysm associated with endocarditis that was caused by Streptococcus pneumoniae serotype 21. The patient, a 12-year-old girl, underwent surgical repair of the aneurysm and was given intravenous antibiotics for 6 weeks. She was doing well at the 6-week follow-up visit. This case is unusual because of the patient's young age at presentation, the absence of predisposing factors, and the isolation of a nonvaccine serotype 21, which revealed the epidemiologic changes of invasive pneumococcal disease. To our knowledge, this is the first reported case of endocarditis caused by this S. pneumoniae serotype.

Keywords: Aneurysm; Streptococcus pneumoniae; endocarditis, bacterial; pediatrics; sinus of Valsalva aneurysm.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Aortic Aneurysm / diagnosis
  • Aortic Aneurysm / microbiology*
  • Aortic Aneurysm / therapy
  • Aortic Rupture / diagnosis
  • Aortic Rupture / microbiology*
  • Aortic Rupture / therapy
  • Aortic Valve / microbiology*
  • Aortic Valve / surgery
  • Child
  • Debridement
  • Echocardiography, Doppler, Color
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / microbiology*
  • Endocarditis, Bacterial / therapy
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Pneumococcal Infections / diagnosis
  • Pneumococcal Infections / microbiology*
  • Pneumococcal Infections / therapy
  • Sinus of Valsalva / microbiology*
  • Sinus of Valsalva / surgery
  • Streptococcus pneumoniae / isolation & purification*
  • Treatment Outcome
  • Vascular Surgical Procedures

Substances

  • Anti-Bacterial Agents