High frequency of copy number alterations in myeloid leukaemia of Down syndrome

Br J Haematol. 2012 Sep;158(6):800-3. doi: 10.1111/j.1365-2141.2012.09224.x. Epub 2012 Jul 7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Child, Preschool
  • Chromosome Aberrations
  • Down Syndrome / complications*
  • Female
  • Gene Amplification
  • Gene Deletion
  • Gene Dosage*
  • Genetic Predisposition to Disease
  • Humans
  • Infant
  • Karyotyping
  • Leukemia, Megakaryoblastic, Acute / etiology
  • Leukemia, Megakaryoblastic, Acute / genetics
  • Leukemia, Myeloid / etiology
  • Leukemia, Myeloid / genetics*
  • Male
  • RNA / genetics
  • Telomerase / genetics
  • Telomere / ultrastructure

Substances

  • telomerase RNA
  • RNA
  • TERT protein, human
  • Telomerase