Concomitant choroidal melanoma and non-hodgkin lymphoma in two adult patients: case report

Case Rep Ophthalmol. 2012 May;3(2):209-13. doi: 10.1159/000339654. Epub 2012 Jun 19.

Abstract

Objective: To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients.

Design: Case report.

Participants: Two patients with yellow creamy infiltrates in fundo.

Intervention: Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye.

Main outcome measures: Histology findings of the enucleated eyes.

Results: One patient showed a choroidal melanoma with a primary non-Hodgkin lymphoma located solely in the affected eye. The other patient showed a systemic non-Hodgkin lymphoma with ocular manifestations concomitant with a choroidal melanoma.

Conclusions: In the presence of yellow creamy infiltrates one should include a choroidal lymphoma in the differential diagnosis even if there is another clear pathologic condition. Furthermore in those cases systemic disease should be excluded.

Keywords: Choroidal melanoma; Non-Hodgkin lymphoma; Uveal melanoma.

Publication types

  • Case Reports