Pregnancy in an intestinal transplant recipient

Obstet Gynecol. 2012 Aug;120(2 Pt 2):497-500. doi: 10.1097/AOG.0b013e31825f01f8.

Abstract

Background: Intestinal transplantation is a relatively new form of therapy for short gut syndrome. Pregnancy after intestinal transplantation is rare.

Case: A 26-year-old small bowel transplant recipient presented for prenatal care. She previously had undergone bariatric surgery and later experienced small bowel necrosis and resection. The resulting short gut syndrome was treated with an isolated small bowel transplant. Medications during this pregnancy included prednisone, esomeprazole, diphenoxylate-atropine, ascorbic acid, tacrolimus, and magnesium supplementation. Throughout her pregnancy, her creatinine level was elevated. Labor was induced at 39 3/7 weeks and resulted in a spontaneous vaginal delivery of a healthy female neonate. Twelve weeks after delivery, the mother was admitted for a rejection reaction that was treated successfully.

Conclusion: A successful pregnancy in an intestinal transplant recipient resulted in delivery of a healthy term newborn.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Ulcer Agents / administration & dosage
  • Creatinine / blood
  • Female
  • Gastrointestinal Agents / administration & dosage
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Infant, Newborn
  • Intestinal Diseases / drug therapy
  • Intestine, Small / transplantation*
  • Labor, Induced
  • Postoperative Period
  • Postpartum Period
  • Pregnancy
  • Pregnancy Complications / drug therapy
  • Pregnancy Complications / prevention & control*
  • Pregnancy Outcome*
  • Short Bowel Syndrome / surgery*
  • Ulcer / drug therapy

Substances

  • Anti-Ulcer Agents
  • Gastrointestinal Agents
  • Immunosuppressive Agents
  • Creatinine