Abstract
Oxacillin-susceptible, mecA-positive Staphylococcus aureus isolates create a treatment challenge for the clinician. In this article, we describe two cases of bacteremia from isolates that carried the mecA gene but were susceptible to oxacillin (oxacillin-susceptible methicillin-resistant S. aureus [OS-MRSA]). DNA microarray analysis was used to characterize these isolates as a mecA-positive, clonal complex 5, pediatric strain and a mecA-positive, clonal complex 8, USA300 strain.
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacteremia / microbiology
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Bacterial Proteins / genetics
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Humans
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Male
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Methicillin-Resistant Staphylococcus aureus / drug effects*
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Methicillin-Resistant Staphylococcus aureus / genetics*
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Microarray Analysis / methods
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Microbial Sensitivity Tests / methods
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Middle Aged
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Oxacillin / pharmacology*
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Penicillin-Binding Proteins
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Staphylococcal Infections / microbiology*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Penicillin-Binding Proteins
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mecA protein, Staphylococcus aureus
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Oxacillin