Cutaneous adverse events associated with heparin

Clin Exp Dermatol. 2012 Oct;37(7):707-11. doi: 10.1111/j.1365-2230.2012.04395.x.

Abstract

Heparin use is associated with various cutaneous reactions, with the most common being immune-mediated skin lesions and bleeding complications. In this review, we compile the dermatological side-effects of heparin reported in the literature, and provide a clear approach to their adequate management.

Publication types

  • Review

MeSH terms

  • Anticoagulants / adverse effects*
  • Drug Eruptions / etiology*
  • Fibrinolytic Agents / adverse effects*
  • Heparin / adverse effects*
  • Humans
  • Hypersensitivity, Delayed / chemically induced*
  • Hypersensitivity, Delayed / diagnosis
  • Hypersensitivity, Delayed / therapy
  • Skin Diseases / chemically induced*
  • Skin Diseases / immunology
  • Skin Diseases / therapy

Substances

  • Anticoagulants
  • Fibrinolytic Agents
  • Heparin