Complete genome sequences of novel rat noroviruses in Hong Kong

J Virol. 2012 Nov;86(22):12435-6. doi: 10.1128/JVI.01976-12.

Abstract

We report two genome sequences of novel noroviruses isolated from fecal swab specimens of brown rats in Hong Kong. The complete genome is approximately 7.5 kb in length and consists of 3 overlapping open reading frames encoding ORF1 polyprotein, VP1, and VP2, respectively. Sequence analysis suggested that these noroviruses should be classified in genogroup V, but they are distinct from other known rodent noroviruses and represent a novel cluster within the genogroup.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caliciviridae Infections / genetics*
  • Cluster Analysis
  • DNA, Viral / genetics
  • Feces
  • Genome, Viral*
  • Hong Kong
  • Molecular Sequence Data
  • Norovirus / genetics*
  • Open Reading Frames
  • Rats
  • Sequence Analysis, DNA

Substances

  • DNA, Viral