The continued emergence of hantaviruses: isolation of a Seoul virus implicated in human disease, United Kingdom, October 2012

Euro Surveill. 2013 Jan 3;18(1):4-7.

Abstract

Following a suspected case of hantavirus in a patientsuffering from acute kidney injury, rodents fromthe patient’s property in Yorkshire and the Humber,United Kingdom (UK) were screened for hantaviruses.Hantavirus RNA was detected via RT-PCR in two Rattusnorvegicus. Complete sequencing and phylogeneticanalysis established the virus as a Seoul hantavirus,which we have provisionally designated as strainHumber. This is the first hantavirus isolated from wildrodents in the UK and confirms the presence of a pathogenicSeoul virus in Europe.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Kidney Injury / diagnosis*
  • Acute Kidney Injury / virology
  • Animals
  • Antibodies, Viral / blood*
  • Communicable Diseases, Emerging / virology
  • Disease Reservoirs
  • Hantavirus Infections / diagnosis
  • Hantavirus Infections / epidemiology*
  • Hantavirus Infections / virology
  • Humans
  • Male
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / analysis*
  • RNA, Viral / genetics
  • Rats
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rodent Diseases
  • Seoul virus / genetics
  • Seoul virus / isolation & purification*
  • Sequence Analysis, DNA
  • United Kingdom / epidemiology

Substances

  • Antibodies, Viral
  • RNA, Viral