Papillary carcinoma thyroid with uveal metastases

Clin Nucl Med. 2013 Feb;38(2):131-4. doi: 10.1097/RLU.0b013e31827a2275.

Abstract

Ocular metastases secondary to thyroid cancer are extremely uncommon, typically affecting the orbit rather than the globe and uvea. Within the uveal structures, the choroid is more commonly involved than the iris and ciliary body. We present a 56-year-old male patient who underwent total thyroidectomy for metastatic papillary thyroid carcinoma (PTC), solid variant. Whole-body(131) I (WBI) scintigraphy was performed and the patient was treated twice with high-dose (131)I therapy. WBI after the second treatment demonstrated right orbital activity. The patient developed sudden onset of right eye diminished vision and was diagnosed with uveal (choroidal) metastases from PTC.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma / pathology*
  • Carcinoma, Papillary
  • Humans
  • Male
  • Middle Aged
  • Radionuclide Imaging
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / pathology*
  • Uveal Neoplasms / diagnostic imaging
  • Uveal Neoplasms / pathology
  • Uveal Neoplasms / physiopathology
  • Uveal Neoplasms / secondary*
  • Whole Body Imaging