Identification of endogenous Coccidioides posadasii contamination of commercial primary rhesus monkey kidney cells

J Clin Microbiol. 2013 Apr;51(4):1288-90. doi: 10.1128/JCM.00132-13. Epub 2013 Jan 30.

Abstract

Here we describe the identification of endogenous Coccidioides posadasii contamination in commercial rhesus monkey kidney (RhMK) cells and the subsequent nationwide alert that reduced the risk of laboratory exposure. This extraordinary event highlights the necessity for laboratories to remain vigilant in the use of appropriate biosafety procedures, particularly when working with unknown pathogens.

MeSH terms

  • Animals
  • Cell Line
  • Coccidioides / genetics
  • Coccidioides / isolation & purification*
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Epithelial Cells / microbiology*
  • Kidney
  • Macaca mulatta
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA, Fungal
  • DNA, Ribosomal Spacer

Associated data

  • GENBANK/KC469982
  • GENBANK/KC469983
  • GENBANK/KC469984