Repeat coronary revascularization after coronary artery bypass surgery in older adults: the Society of Thoracic Surgeons' national experience, 1991-2007

Circulation. 2013 Apr 23;127(16):1656-63. doi: 10.1161/CIRCULATIONAHA.113.001882. Epub 2013 Mar 26.

Abstract

Background: A major advantage of coronary artery bypass graft surgery (CABG) relative to percutaneous coronary intervention is its durability, yet there is a paucity of information on rates and predictors of repeat coronary revascularization after CABG in the modern era.

Methods and results: We included patients ≥65 years from the Society of Thoracic Surgeons' National Adult Cardiac Surgery Database who were undergoing first-time isolated CABG from 1991 to 2007 (n=723 134, median age 73 years). After linking to Medicare claims data, long-term outcomes of CABG (up to 18 years after surgery) were examined by use of cumulative incidence curves. Multivariable Cox proportional hazard analysis was used to identify factors associated with 1- and 5-year repeat revascularization trends and variability. We found that the overall 18-year survival rate was 20%. Cumulative incidences of any repeat revascularization (percutaneous coronary intervention or CABG, yet most often percutaneous coronary intervention) were 2%, 7%, 13%, and 16% at 1, 5, 10, and 18 years after surgery, respectively. The rates of repeat CABG procedures were quite low for all time points (0.1%, 0.6%, 1.3%, and 1.7%, respectively). Female sex, disease severity represented by a history of percutaneous coronary intervention, preoperative dialysis, and partial revascularization were strongly associated with a higher revascularization rate, whereas advanced age, left main disease, and smoking were associated with a lower rate. There was approximately a 2-fold variation in repeat revascularization rates across centers at 1 year (interquartile range 1.7-3.6%) and 5 years (interquartile range 6.7-12.0%).

Conclusions: Repeat revascularization is performed infrequently among older patients who undergo CABG; however, these rates vary substantially by patient subgroups and among providers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Comorbidity
  • Coronary Artery Bypass / statistics & numerical data*
  • Coronary Restenosis / surgery*
  • Coronary Restenosis / therapy
  • Databases, Factual / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Kidney Diseases / epidemiology
  • Kidney Diseases / therapy
  • Male
  • Medicaid / statistics & numerical data
  • Medicare / statistics & numerical data
  • Obesity / epidemiology
  • Percutaneous Coronary Intervention / statistics & numerical data*
  • Postoperative Complications / mortality
  • Proportional Hazards Models
  • Renal Dialysis / statistics & numerical data
  • Reoperation / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • Smoking / epidemiology
  • Societies, Medical
  • Survival Rate
  • Thoracic Surgery
  • United States / epidemiology