Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII

Thromb Haemost. 2013 Jul;110(1):202-4. doi: 10.1160/TH13-01-0053. Epub 2013 May 2.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • ADAM Proteins / metabolism*
  • ADAMTS13 Protein
  • Factor VIII / metabolism*
  • Humans
  • Mutation
  • Proteolysis*
  • von Willebrand Disease, Type 2 / genetics
  • von Willebrand Disease, Type 2 / metabolism*
  • von Willebrand Factor / genetics
  • von Willebrand Factor / metabolism*

Substances

  • von Willebrand Factor
  • Factor VIII
  • ADAM Proteins
  • ADAMTS13 Protein
  • ADAMTS13 protein, human