Accuracy of point-of-care ultrasound for diagnosis of skull fractures in children

Pediatrics. 2013 Jun;131(6):e1757-64. doi: 10.1542/peds.2012-3921. Epub 2013 May 20.

Abstract

Objective: To determine the test performance characteristics for point-of-care ultrasound performed by clinicians compared with computed tomography (CT) diagnosis of skull fractures.

Methods: We conducted a prospective study in a convenience sample of patients ≤21 years of age who presented to the emergency department with head injuries or suspected skull fractures that required CT scan evaluation. After a 1-hour, focused ultrasound training session, clinicians performed ultrasound examinations to evaluate patients for skull fractures. CT scan interpretations by attending radiologists were the reference standard for this study. Point-of-care ultrasound scans were reviewed by an experienced sonologist to evaluate interobserver agreement.

Results: Point-of-care ultrasound was performed by 17 clinicians in 69 subjects with suspected skull fractures. The patients' mean age was 6.4 years (SD: 6.2 years), and 65% of patients were male. The prevalence of fracture was 12% (n = 8). Point-of-care ultrasound for skull fracture had a sensitivity of 88% (95% confidence interval [CI]: 53%-98%), a specificity of 97% (95% CI: 89%-99%), a positive likelihood ratio of 27 (95% CI: 7-107), and a negative likelihood ratio of 0.13 (95% CI: 0.02-0.81). The only false-negative ultrasound scan was due to a skull fracture not directly under a scalp hematoma, but rather adjacent to it. The κ for interobserver agreement was 0.86 (95% CI: 0.67-1.0).

Conclusions: Clinicians with focused ultrasound training were able to diagnose skull fractures in children with high specificity.

Keywords: emergency medicine; head trauma; pediatrics; skull fracture; ultrasound.

Publication types

  • Validation Study

MeSH terms

  • Child
  • Child, Preschool
  • Emergency Service, Hospital
  • Female
  • Humans
  • Male
  • Point-of-Care Systems*
  • Prospective Studies
  • Sensitivity and Specificity
  • Skull Fractures / diagnostic imaging*
  • Tomography, X-Ray Computed
  • Ultrasonography