Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

J Clin Oncol. 2013 Nov 10;31(32):e439-42. doi: 10.1200/JCO.2012.47.7521. Epub 2013 Sep 16.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / therapeutic use
  • Antigens, Neoplasm / immunology*
  • Antineoplastic Agents / therapeutic use
  • DNA, Neoplasm / analysis
  • Exome* / genetics
  • Humans
  • Ipilimumab
  • Lymphocytes, Tumor-Infiltrating / immunology*
  • Male
  • Melanoma / drug therapy
  • Melanoma / genetics*
  • Melanoma / immunology
  • Middle Aged
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / genetics*
  • Skin Neoplasms / immunology
  • T-Lymphocytes / immunology*

Substances

  • Antibodies, Monoclonal
  • Antigens, Neoplasm
  • Antineoplastic Agents
  • DNA, Neoplasm
  • Ipilimumab