Methotrexate in refractory bilateral juvenile temporal arteritis: Report of a case

Mod Rheumatol. 2016;26(2):276-7. doi: 10.3109/14397595.2013.850147. Epub 2013 Nov 4.

Abstract

Juvenile temporal arteritis is a rare inflammatory disease of the temporal arteries that affects young adults. The clinical course is benign and the surgical excision of the affected artery is usually curative. Here we report a case of bilateral juvenile temporal arteritis with significant peripheral eosinophilia and elevated IgE, refractory to surgical excision and even to a short course of corticosteroids. Methotrexate, added as a steroid-sparing agent, resulted in a good disease control.

Keywords: Juvenile arteritis; Methotrexate; Temporal arteritis.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Adult
  • Antirheumatic Agents / therapeutic use*
  • Giant Cell Arteritis / drug therapy
  • Giant Cell Arteritis / pathology
  • Giant Cell Arteritis / surgery
  • Giant Cell Arteritis / therapy*
  • Humans
  • Male
  • Methotrexate / therapeutic use*
  • Retreatment
  • Temporal Arteries / pathology
  • Temporal Arteries / surgery*
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Antirheumatic Agents
  • Methotrexate