Is anti-D immunoglobulin still a frontline treatment option for immune thrombocytopenia?

Hematology Am Soc Hematol Educ Program. 2013:2013:283-5. doi: 10.1182/asheducation-2013.1.283.

Abstract

A 5-year-old boy presents with platelet count of 2×10(9)/L and clinical and laboratory evidence of immune thrombocytopenia. He has epistaxis and oral mucosal bleeding. Complete blood count reveals isolated thrombocytopenia without any decline in hemoglobin and he is Rh+. You are asked if anti-D immunoglobulin is an appropriate initial therapy for this child given the 2010 Food and Drug Administration "black-box" warning.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Epistaxis* / blood
  • Epistaxis* / diagnosis
  • Epistaxis* / drug therapy
  • Female
  • Humans
  • Immunoglobulin D*
  • Male
  • Oral Hemorrhage* / blood
  • Oral Hemorrhage* / diagnosis
  • Oral Hemorrhage* / drug therapy
  • Platelet Count
  • Purpura, Thrombocytopenic, Idiopathic* / blood
  • Purpura, Thrombocytopenic, Idiopathic* / diagnosis

Substances

  • Immunoglobulin D