Impact of Down syndrome on the performance of neonatal screening assays for severe primary immunodeficiency diseases

Affiliations

• ¹ Department of Pediatrics, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
• ² Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden; Translational Centre for Regenerative Medicine, University of Leipzig, Leipzig, Germany; ImmunoDeficiencyCenter Leipzig at Hospital St Georg gGmbH Leipzig, Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Leipzig, Germany.
• ³ Department of Pediatrics, Máxima Medical Center, Veldhoven, The Netherlands.
• ⁴ Department of Pediatrics, Juliana Children's Hospital, The Hague, The Netherlands.
• ⁵ Division of Metabolic Diseases, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.
• ⁶ Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden.
• ⁷ Department of Pediatrics, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands. Electronic address: e.d.vries@jbz.nl.