Cilostazol enhances mobilization and proliferation of endothelial progenitor cells and collateral formation by modifying vasculo-angiogenic biomarkers in peripheral arterial disease

Int J Cardiol. 2014 Mar 15;172(2):e371-4. doi: 10.1016/j.ijcard.2013.12.295. Epub 2014 Jan 11.
No abstract available

Keywords: Angiogenesis; Biological markers; Cilostazol; Peripheral arterial disease; Progenitor cells.

Publication types

  • Letter
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / blood
  • Cell Movement / drug effects
  • Cell Movement / physiology
  • Cell Proliferation / drug effects*
  • Cilostazol
  • Collateral Circulation / drug effects
  • Collateral Circulation / physiology
  • Double-Blind Method
  • Endothelial Cells / drug effects*
  • Endothelial Cells / metabolism
  • Follow-Up Studies
  • Humans
  • Neovascularization, Pathologic / blood
  • Neovascularization, Pathologic / drug therapy*
  • Neovascularization, Pathologic / pathology
  • Peripheral Arterial Disease / blood
  • Peripheral Arterial Disease / drug therapy*
  • Peripheral Arterial Disease / pathology
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prospective Studies
  • Stem Cells / drug effects*
  • Stem Cells / metabolism
  • Tetrazoles / pharmacology
  • Tetrazoles / therapeutic use*

Substances

  • Biomarkers
  • Platelet Aggregation Inhibitors
  • Tetrazoles
  • Cilostazol