Bioethics of organ transplantation

Cold Spring Harb Perspect Med. 2014 Mar 1;4(3):a015685. doi: 10.1101/cshperspect.a015685.

Abstract

As the ability to transplant organs and tissues has grown, the demand for these procedures has increased as well--to the point at which it far exceeds the available supply creating the core ethical challenge for transplantation--rationing. The gap between supply and demand, although large, is worse than it appears to be. There are two key steps to gaining access to a transplant. First, one must gain access to a transplant center. Then, those waiting need to be selected for a transplant. Many potential recipients do not get admitted to a program. They are deemed too old, not of the right nationality, not appropriate for transplant as a result of severe mental impairment, criminal history, drug abuse, or simply because they do not have access to a competent primary care physician who can refer them to a transplant program. There are also financial obstacles to access to transplant waiting lists in the United States and other nations. In many poor nations, those needing transplants simply die because there is no capacity or a very limited capacity to perform transplants. Although the demand for organs now exceeds the supply, resulting in rationing, the size of waiting lists would quickly expand were there to suddenly be an equally large expansion in the number of organs available for transplantation. Still, even with the reality of unavoidable rationing, saving more lives by increasing organ supply is a moral good. Current public policies for obtaining organs from cadavers are not adequate in that they do not produce the number of organs that public polls of persons in the United States indicate people are willing to donate.

Publication types

  • Review

MeSH terms

  • Attitude to Health
  • Health Care Rationing / ethics
  • Health Policy
  • Humans
  • Motivation
  • Organ Transplantation / ethics*
  • Public Opinion
  • Tissue Donors / supply & distribution
  • Tissue and Organ Procurement / ethics
  • Tissue and Organ Procurement / organization & administration