Management of neonatal herpes simplex virus infection and exposure

Arch Dis Child Fetal Neonatal Ed. 2014 May;99(3):F240-4. doi: 10.1136/archdischild-2013-303762. Epub 2014 Mar 3.

Abstract

Neonatal herpes simplex virus (HSV) infections are rare but are associated with significant morbidity and mortality. Advances in diagnostic modalities to identify these infants, as well as the development of safe and effective antiviral therapy, have revolutionised the management of affected infants. This review will summarise the epidemiology of neonatal HSV infections and discuss the management of infants with HSV exposure and infection.

Keywords: PCR; acyclovir; genital herpes; neonatal herpes.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adult
  • Antiviral Agents / administration & dosage*
  • Female
  • Herpes Simplex* / diagnosis
  • Herpes Simplex* / drug therapy
  • Herpes Simplex* / epidemiology
  • Herpes Simplex* / transmission
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Male
  • Maternal Exposure / statistics & numerical data*
  • Pregnancy
  • Pregnancy Complications, Infectious* / diagnosis
  • Pregnancy Complications, Infectious* / drug therapy
  • Pregnancy Complications, Infectious* / epidemiology
  • Pregnancy Complications, Infectious* / etiology
  • Prognosis

Substances

  • Antiviral Agents

Supplementary concepts

  • Neonatal herpes